The Day One Project is interested in addressing the following areas: Artificial Intelligence R&D, Opportunities and Risk Mitigation. The next administration must prioritize responsible AI innovation to maintain the U.S. leadership in technology, while adhering to ethical guidelines and standards for AI development and deployment. What key investments should the federal government make to advance AI for the public good in major domains of opportunity? How can we operationalize and scale existing policy tools and frameworks that can guide AI development, safety, transparency, and accountability