Scientists at the University of Rochester Medical Center have devised a new bioluminescence imaging technique to create highly detailed and visually striking images of the movement of oxygen in mice’s brains. This technique could assist scientists in precisely studying forms of hypoxia in the brain, such as the denial of oxygen to the brain that occurs during a stroke or heart attack. The new approach uses luminous proteins injected into cells by a virus that delivers instructions to cells to produce a luminescent protein as an enzyme.