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How to Block SOX17 in Colorectal Cancer
In mice, researchers observed a dramatic increase in the tumors’ expression of SOX17. This gene encodes a transcription factor that is normally active only during embryonic development. SoX17 prevents cells from synthesizing the receptor that normally detects interferon gamma. Without these receptors, cancerous and precancerous cells can simply ignore messages from the immune system.
#TECHNOLOGY #English #ID
Read more at MIT Technology Review
Hispanic and Latino Business Owners - Ascend Program
The Lansing Area Economic Partnership (LEAP) has launched its Ascend Program. Each one gives entrepreneurs from all different walks of life a chance to grow their businesses. The program is the next step in that effort, this time focusing on a group still facing obstacles to business ownership.
#BUSINESS #English #ID
Read more at WILX
Ukraine’s Cyber War Against Russia
Russia’s full-scale invasion of Ukraine in February 2022 marked the start of what should be termed – in view of the unprecedented scale and sophistication of cyber operations. Ukraine showcased to the international community not only the critical importance of robust cyber defenses but also the complexity involved in their implementation. The following day, Russia escalated its cyber war, conducting a significant cyberattack that affected various Ukrainian government institutions and resulted in dozens of government websites being controlled by hackers.
#WORLD #English #ID
Read more at Asia Times
Maternal Dengue and Health Outcomes of Children
Dengue fever is the most prevalent mosquito-borne disease globally. It poses a threat to half of the world's population. Since January 2024, Brazil has reported more than 3.5 million cases. This is the largest dengue outbreak on record.
#HEALTH #English #IN
Read more at Medical Xpress
UN Human Rights Office Calls For Inquiry Into Two Mass Graves Found in Gaza
Palestinian Civil Defense said it had found a mass grave containing 283 bodies on the grounds of Nasser Hospital in Khan Younis. Israel’s military declined to address those claims on Tuesday, and they could not be independently verified. On Tuesday, hours after the top U.N. human rights official called for an inquiry into the mass graves, the Israeli military said its forces had exhumed and examined them as part of an effort to locate hostages.
#HEALTH #English #IN
Read more at The New York Times
Common Mental Disorders Among Adolescents in Delhi
At least 34% of the 491 adolescents residing in an urban area in Delhi have been found to be suffering from common mental disorders. The study was conducted in Dakshinpuri Extension of Ambedkar Nagar, an urban resettlement colony in South East Delhi.
#HEALTH #English #IN
Read more at The Times of India
Next Science Ltd (AU:NXS) Update
Next Science Ltd is confident in achieving FY24 revenue guidance of US$36m-$40m. This strategic shift includes transitioning to a flexible, commission-based sales team and capitalizing on new market opportunities to drive future growth.
#SCIENCE #English #IN
Read more at TipRanks
IndyCar - The Biggest Loser in Free Agency
IndyCar, after just two races, is suddenly rife with rumors about driver free agency. The Arrow McLaren driver dislocated his wrist and tore tendons in a mountain biking crash a month before the season opener. When the 22-year-old Malukas misses Sunday’s race at Barber Motorsports Park in Alabam, he will have been out of the car for six outings that includes an exhibition race and an Indianapolis 500 test.
#SPORTS #English #IN
Read more at News18
The Carolina Panthers Traded For Wide Receiver Diontae Johnson
The Carolina Panthers spent $150 million upgrading their offensive line and traded for wide receiver Diontae Johnson in an attempt to help quarterback Bryce Young maximize his potential. The Panthers invested a lot in Young last year, and it’s absolutely vital to their future that he shows progression. It’s a move that ultimately costly Carolina the No. 1 overall pick in this week’s NFL draft after the Panthers finished 2-15, the worst record in the league.
#SPORTS #English #IN
Read more at News18
Buffalo Sabres GM Lindy Ruff Laughs
Lindy Ruff is the last coach to guide the Sabres to the playoffs. He spent his first 10-plus NHL seasons as a coach for the team before being fired a month into the lockout-shortened 2013 season. “I’m humbled by the opportunity that I’m getting,” Ruff said.
#SPORTS #English #IN
Read more at News18