I-GS-100 iyinhlanganisela ye-AAV9 enekhodi yofuzo lwe-NGLY1 yomuntu. Ithole ukubizwa kwezidakamizwa ze-orphan kusuka ku-US Food and Drug Administration kanye ne-European Medicine Agency (EMA) Ukwelashwa futhi kwathola ukubizwa kwezifo ezingavamile zezingane ze-FDA ngo-2021 kanye nokuqokwa kwe-fast track ngonyaka odlule.