Kwiphando lwakutsha nje olwenziwe kwiJAMA Network Open, abaphandi baseUnited States of America (US) baphande ngokunxulumana phakathi kwetyala lezonyango kunye neziphumo zempilo yabemi base-US. Bafumanisa ukuba ityala lezonyango linxulunyaniswa nemeko yempilo engcono kunye nokwanda kokufa ngaphambi kwexesha kunye nokufa kwabemi. Le tyala linxulunyaniswa nefuthe elibi kwintlalontle, njengokulibaziseka kwezempilo, ukungabambeki kwelayisensi, kunye nokwanda kokungakhuselekanga kokutya kunye nezindlu.
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