GS-100 i mutshunguri wa AAV9 loyi a nga na NGLY1 gene. Yi amukerile ku va murhi wa xivelekelo hi va U.S. Food and Drug Administration na European Medicine Agency (EMA). Vutshunguri lebyi byi tlhele byi amukeriwa hi va FDA's rare paediatric disease designation hi 2021 na fast track designation n'wexemu.