GS-100 ke recombinant AAV9 vector e ngolisang gene ea NGLY1 ea motho. E amohetse lebitso la lithethefatsi la likhutsana ho tsoa ho US Food and Drug Administration le European Medicine Agency (EMA) Phekolo e boetse e fumane lebitso la FDA la lefu le sa tloaelehang la bana ka 2021 le lebitso la tsela e potlakileng selemong se fetileng.